What Are the Options?

Chronic pain in cats is more than just discomfort—it’s a serious quality-of-life issue. Arthritis is one of the most common causes of pain in older cats, and it can affect everything from walking and grooming to mood and sleep.

The good news? There are now more safe and effective pain relief options for cats than ever before. Here’s an overview of what you and your veterinarian might consider.

Solensia® (frunevetmab)

• What it is: The first and only FDA-approved medication for arthritis pain in cats.
• How it works: Blocks a protein called nerve growth factor (NGF), which plays a big role in chronic pain.
• How it’s given: A monthly injection at your vet’s office.
• What to expect: Many cats show improved activity and comfort. Possible side effects include mild vomiting, itching, or scabbing at the injection site.

NSAIDs (Non-Steroidal Anti-Inflammatory Drugs)

• What they do: Reduce inflammation and joint pain.
• Examples: Meloxicam (Metacam®), Robenacoxib (Onsior®).
• Availability: Approved for long-term use in some countries, but not in the U.S. (your vet may use them off-label).
• Safety tips: Long-term use requires regular monitoring with blood work, and cats must stay well hydrated to avoid kidney stress.

Oral Pain Medications

Used off-label but sometimes helpful for feline arthritis:

• Gabapentin: Targets nerve pain; can also reduce anxiety. (May cause sleepiness.)
• Amantadine: Helps with “pain sensitization” and may improve quality of life.
• Tramadol: Occasionally used, but many cats dislike the taste and may experience stomach upset.

Nutrition and Supplements

• Omega-3 fatty acids: Shown to help reduce inflammation; available in special diets or high-quality supplements.
• Adequan® injections: Support joint health and may slow arthritis progression (not officially approved for cats but used by many vets).
• What to avoid: Glucosamine and chondroitin—studies show they don’t work in cats. Always check with your vet before trying alternative options like CBD.

Beyond Medication

Managing pain also means supporting your cat’s environment and emotional well-being:

• Provide soft bedding, ramps, and easy access to food, water, and litter.
• Keep routines predictable to reduce stress.
• If vet visits are stressful, ask about calming pre-visit medications (like gabapentin or Bonqat) to make the experience easier.

The Bottom Line

Pain is not a normal part of aging. If your cat is slowing down, skipping favorite perches, or grooming less, it may be arthritis pain—not “just getting older.” With today’s treatment options, you and your veterinarian can create a plan that helps your cat stay more comfortable, mobile, and happy for years to come.